Media

January 4, 2019

Akero Therapeutics to Present at the 37th Annual J.P. Morgan Healthcare Conference

President and CEO to share plans for the company’s lead clinical candidate

San Francisco, CA – Akero Therapeutics, Inc., a clinical-stage biotechnology company focused on developing and commercializing transformative treatments for patients with serious metabolic diseases with high unmet medical need, with an initial focus on non-alcoholic steatohepatitis (NASH), today announced the company will present at the 37th Annual J.P. Morgan Healthcare Conference in San Francisco, CA next week.

Akero’s President and CEO Andrew Cheng, MD, PhD, will share plans for the company’s lead clinical candidate, AKR-001 on Tuesday, January 8, 2019 at 9:30 a.m. PT. The presentation will be held in Elizabethan Room C at the Westin St. Francis.

The company’s lead product candidate, AKR-001, is a novel, long-acting fibroblast growth factor 21 (FGF21) analog in-licensed from Amgen Inc. AKR-001 has been shown to reproduce the balanced pharmacology of native FGF21, a metabolic hormone harnessed and naturally recruited by the body to restore health to cells in distress, including in the liver. With specific potency at receptors FGFR1c, 2c and 3c but not FGFR4, AKR-001 has the potential to substantially reduce liver fat, cellular stress, inflammation and reverse fibrosis in patients with NASH and to improve risk factors of cardiovascular disease, by reducing triglycerides and non-HDL cholesterol. In two Phase 1 clinical trials in patients with Type 2 diabetes, AKR-001 was well-tolerated and shown to improve insulin sensitivity and lipoprotein markers with once-weekly subcutaneous dosing. The company is on track to initiate a Phase 2 clinical trial for AKR-001 in NASH patients in the middle of 2019.

Media Contact: 

Lissette Steele
Verge Scientific Communications
202.930.4762
lsteele@vergescientific.com


About AKR-001

AKR-001 is an Fc-FGF21 fusion protein that has been engineered to mimic the biological activity profile of native FGF21, an endogenous hormone that regulates lipid and energy metabolism, and is secreted throughout the body to alleviate cellular stress. Observations from clinical trials of AKR-001 and other FGF analogs point to AKR-001’s potential to reduce liver fat, cellular stress, inflammation and fibrosis in people with non-alcoholic steatohepatitis (NASH), as well as to improve risk factors of cardiovascular disease, the principal cause of death among NASH patients.

About Akero Therapeutics

Akero Therapeutics is a clinical-stage biotechnology company focused on the development and commercialization of transformative treatments for patients with serious metabolic disease with high unmet medical need by restoring metabolic balance. Akero’s lead program AKR-001, an engineered Fc-FGF21 fusion protein, is being evaluated in clinical trials as a potential leading fibroblast growth factor analog for treatment of NASH, a disease without any approved therapies.


Media Contact

Lissette Steele
Verge Scientific Communications
202.930.4762
lsteele@vergescientific.com

Investor Contact
Christina Tartaglia
Stern IR, Inc.
212.362.1200
Christina.tartaglia@sternir.com

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