3 Akero employees smiling and conversing in a communal space

Leadership

Our leadership team has been involved in the research, development, and commercialization of more than 20 global medicines.

Our team’s collective experience, which includes prior leadership roles at leading biotechnology and pharmaceutical companies, positions us to advance and broaden our pipeline not only through clinical evaluation but also commercial launch.

Dominick Villani, Ph.D.

Vice President, Quality

Dominick Villani is vice president of quality assurance at Akero and brings more than 22 years of experience in the biotechnology, biodefense vaccines, pharmaceuticals (sterile and non-sterile), and medical-device sectors. He has held senior roles with Amgen, Amylin, AstraZeneca, Bristol-Myers Squibb, Bioport, and Enable Injections, defining, building, and managing global requirements within high-volume manufacturing, microbiological quality control, quality assurance, and regulatory affairs programs. Dominick studied general biological sciences with an emphasis in microbiology at the California Lutheran University in Thousand Oaks, CA.

Libette Luce

Vice President, Regulatory Affairs

Libette Luce is vice president of regulatory affairs at Akero. She brings more than 20 years of experience in the pharmaceutical industry, with more than 15 years specializing in global regulatory affairs across multiple therapeutic areas, including cardiovascular, dermatology, GI, metabolic, and ophthalmic/retinal disease. Libette joins us from Innocoll Biotherapeutics, where she was VP, head of regulatory affairs leading development and commercial global regulatory initiatives for the company’s product portfolio in the non-opioid pain management space. Prior to Innocoll, she was executive director of global regulatory affairs at Bausch Health Companies, Inc., leading the management of product portfolios for Bausch’s business units, GI (Salix Pharmaceuticals), dermatology (Dow Pharmaceuticals) and ophthalmology (Bausch and Lomb, Inc.). She also has held global regulatory positions at Allergan (Abbvie), Forest Laboratories (Abbvie), Roche, and Schering-Plough (Merck). Libette holds a MA in diplomacy and International Relations from Seton Hall University and a BA Arts in political science and international studies from the University of Miami.

Matthew Johnson, Ph.D.

Vice President, Drug Substance

Matthew Johnson is vice president, drug substance, at Akero. Matthew has over 20 years of experience bringing biopharmaceutical products from early-phase through commercialization at roles of increasing responsibility. He has extensive late-phase and commercialization biologics experience gained at both Biogen and Wyeth/Pfizer for therapeutic protein and vaccine products development and manufacturing. Most recently, prior to joining Akero, he led the manufacturing, tech transfer and validation efforts for multiple cell therapies under clinical development at Cellectis Biologics. At the Duke Human Vaccine Institute, Matthew was the GMP Program Director and Principal Investigator overseeing GMP development and production of all early-phase candidates across multiple vaccine modalities and co-published a paper establishing a mRNA vaccine production platform with Nobel Laureate Drew Weissman of the University of Pennsylvania. Matthew holds a B.S. in Biological Engineering from Cornell University, and a Ph.D. in Chemical Engineering and a M.B.A. from North Carolina State University.

Meena Jain, M.D., Ph.D.

Vice President, Clinical Development

Meena Jain is vice president of clinical development at Akero. She brings more than 17 years of pharmaceutical industry experience as a physician-scientist with expertise spanning multiple therapeutic areas and platforms. Meena joined Akero from Spark Therapeutics, where she led the clinical development of novel gene therapy programs for rare lysosomal storage disorders. Prior to that, she held various leadership positions at CSL Behring and MedImmune (now AstraZeneca), focusing on the development of diverse assets across a broad spectrum of indications, including metabolic disease and MASH. She also served as head of medical affairs at Napp Pharmaceuticals in the UK. Meena holds medical and doctorate degrees from the University of Cambridge, UK, and is both a member of the Royal College of Physicians and a fellow of its Faculty of Pharmaceutical Medicine. Before transitioning to industry, she completed her residency in internal medicine within the UK’s National Health Service (NHS).

Mark Iwicki

Chairman

Mark Iwicki has more than 25 years of experience leading all aspects of R&D and commercialization in the biopharmaceutical industry. He is the chairman and CEO of Kala Pharmaceuticals, and was previously the CEO of Civitas Therapeutics, which was acquired by Acorda Therapeutics. Prior to Civitas, Mark served as the president and chief executive officer of Blend Therapeutics; president and chief executive officer of Sunovion Pharmaceuticals; and president and chief operating officer at Sepracor, which was acquired in 2009. During his previous tenure at Novartis, Mark served as business unit head and managed the cardiovascular, diabetes, arthritis, bone, gastrointestinal, HRT, infectious diseases, and urology therapeutic areas. Preceding these roles, Mark held management positions at Merck and Astra Merck. Mark serves on the boards of Kala Pharmaceuticals, Aimmune Therapeutics, Merus, Nimbus Therapeutics, and Pulmatrix. Mark holds a B.S. from Ball State University and an MBA from Loyola University.

Andrew Cheng, M.D., Ph.D.

President & Chief Executive Officer

Dr. Cheng has served as Akero's president and chief executive officer since September 2018. Before joining the company, he served for 19 years at Gilead Sciences, where his last role was chief medical officer. During his tenure, he was responsible for the clinical development of the HIV program resulting in 11 FDA/EMA approved products. Dr. Cheng serves on the board of directors of Vera Therapeutics. He previously served on the board of directors of MorphoSys (acquired by Novartis), Arbutus Biopharma, and privately held Syntimmune (acquired by Alexion). Dr. Cheng holds a B.A. in biology from Johns Hopkins University and an M.D. and Ph.D. in cellular and molecular biology from Columbia University College of Physicians and Surgeons. He completed his internal medicine residency at UCLA and was board certified in internal medicine.

Graham Walmsley, M.D., Ph.D.

Independent Board Member

Dr. Graham Walmsley is a co-founder and managing partner of Logos Capital, a fundamental biotechnology-focused hedge fund that combines in-house data analytics with scientific and clinical expertise to identify transformative therapies in healthcare. Based in San Francisco, Logos combines expertise across medical, scientific, and statistical disciplines to expand the depth of diligence in identifying compelling investment ideas and uncorrelated-market returns. Before Logos, Graham was a principal at Versant Ventures, where he invested in biotechnology companies across four funds totaling more than $1.5 billion in AUM. While at Versant, he served as a board director, built and launched multiple companies, and was head of business development for Jecure Therapeutics through its acquisition by Roche AG. Graham has more than 60 scientific publications and holds an M.D. and Ph.D. from Stanford University School of Medicine.

Jane Pritchett Henderson

Independent Board Member

Jane Pritchett Henderson has more than 28 years of experience in healthcare life sciences with a unique combination of extensive investment banking, corporate biopharmaceutical senior management, and board director experience, making her a trusted advisor to numerous companies. Jane currently is the chief financial officer of Adagio Therapeutics. Prior to joining Adagio, she served as chief financial officer at Turnstone Biologics, chief financial officer and senior vice president of corporate development at Voyager Therapeutics, and chief financial and business officer at Kolltan Pharmaceuticals until its sale to Celldex Therapeutics. Previously, Jane served in various financial and business development leadership roles at ISTA Pharmaceuticals, Axerion Pharmaceuticals, and Panacos Pharmaceuticals. Jane has an extensive healthcare investment banking background in addition to her industry experience, including execution of more than 95 M&A, advisory, and financing transactions over a nearly 20-year career at HSBC, CIBC, Lehman Brothers, and Salomon Brothers, collectively. Jane currently serves on the board of directors of IVERIC Bio (formerly Ophthotech) and Sesen Bio (formerly Eleven Biotherapeutics). Jane holds a BS from Duke University.

Judy Chou, Ph.D.

Independent Board Member

Judy Chou is a biotech industry leader with a 25-year track record of driving drug development and biomanufacturing successes in established and emerging growth biopharmaceutical companies. Dr. Chou is currently president and CEO of AltruBio, Inc., a company focused on developing novel therapeutics for immunological diseases. Prior to AltruBio, she was senior vice president and global head of Biotech at Bayer Pharmaceuticals, where she oversaw a more than $3 billion biotechnology product portfolio and led drug development and launch activities for the companies’ biologics pipeline. Earlier in her career, Dr. Chou held senior pharmaceutical operations and manufacturing roles at Pfizer, Inc., formerly Medivation, and Tanvex Biopharma, Inc. Before joining the industry, Dr. Chou was a research faculty member at Harvard University Medical School, focused on cell biology and neuroscience research. She received her Ph.D. from Yale University and completed her post-doctoral training at Max-Planck Institute in Germany.

Jonathan Young, Ph.D, J.D.

Chief Executive Officer

Jonathan Young is co-founder and chief executive officer of Akero. Prior to co-founding Akero, Jonathan held roles as a venture partner at Apple Tree Partners (ATP) and general counsel and vice president of policy/advocacy at Braeburn Pharmaceuticals, Inc., an ATP portfolio company. He previously worked as partner and general counsel of FoxKiser, a Washington, DC, law firm specializing in regulatory approval and lifecycle management for pharmaceutical and biotechnology companies. Jonathan is an advocate for policies that empower patients and people with disabilities to reach their life goals. In 2009, he was appointed by President Barack Obama, and confirmed by the U.S. Senate, to serve as chairman of the National Council on Disability, an independent federal agency advising the president and Congress on disability policy. He previously coordinated White House disability policy for President Bill Clinton. He currently serves on the board of directors of the MedStar Health Research Institute. Jonathan holds a Ph.D. in American history from the University of North Carolina at Chapel Hill, and a J.D. from Yale Law School.

Reshma Shringarpure, Ph.D.

Vice President, Clinical Research & Medical Affairs

Reshma Shringarpure is vice president of clinical research and medical affairs at Akero. She brings more than 15 years of experience in clinical and medical affairs across multiple therapeutic areas, including GI, non-viral liver disease, and metabolic disease. Reshma joins Akero from Intercept Pharmaceuticals, where she was the clinical lead for the company’s late-stage NASH program and was integral to achieving several company milestones toward registrational filings in the US and Europe. Prior to joining Intercept, she was the director of medical affairs at Santarus, which was subsequently acquired by Salix Pharmaceuticals. Leading up to this role, Reshma held several scientific positions at Prometheus Therapeutics and Diagnostics as the clinical and medical affairs lead focused on Prometheus’ GI portfolio. She started her pharmaceutical career at Amylin Pharmaceuticals focusing on metabolic diseases and is a co-author of several peer-reviewed publications. Reshma holds a doctorate in molecular biology from the University of Southern California and completed her post-doctoral training at Dana Farber Cancer Institute, Harvard Medical School.

Sean Doyle

Vice President, Operations

Sean Doyle is vice president of operations at Akero and brings more than 20 years of experience in information technology, operations, and infrastructure leadership within the biotechnology and technology sectors. In addition to leading operational strategy, he also oversees human resources functions, including managing recruitment and guiding talent strategy, organizational development, and employee relations to support Akero’s continued growth and integration efforts. Prior to joining Akero, Sean held senior IT and operations leadership roles at Lyell Immunopharma, Achaogen, and other organizations, where he led enterprise technology strategy, compliance initiatives, and operational scaling to support company growth and key milestones.

Tom Ross

Senior Vice President, Head of Legal

Tom Ross is senior vice president, head of legal, at Akero. Tom has more than 15 years of life-sciences experience, including most recently as Head of U.S. Legal for an Australian-based public biotech (cross-listed on NASDAQ: MESO) where he played a central role in helping the company receive the first-ever FDA approval of a mesenchymal stromal cell (MSC) product as well as the first approval of a therapy for pediatric steroid refractory acute graft-versus-host disease (SR-aGVHD), a rare and serious condition. Before then, Tom was the Head of Litigation & Investigations and Global Chief FDA Compliance Counsel at Lupin Pharmaceuticals, a federal prosecutor at the U.S. Department of Justice where he represented FDA in civil and criminal litigation and investigations, and an FDA compliance and enforcement attorney at the international law firm Sidley Austin. Tom holds a B.A. in Political Science from the University of Chicago, a Master’s in Psychoanalytic Studies from Trinity College Dublin (Ireland), and a JD from Cornell Law School.

Yasmine Rafidi

Vice President, Financial Planning & Analysis

Yasmine is vice president of financial planning & analysis at Akero and brings more than 18 years of experience in finance and accounting. Prior to joining Akero, Yasmine served in various finance roles supporting different therapeutic areas, functions, and leaders at Gilead, FivePrime, and Adamas. She is a licensed CPA in California (inactive) and holds bachelor of science degrees in accounting and corporate finance.

Yung-Hsiang Kao

Vice President, Analytical Development and Quality Control

Yung-Hsiang Kao serves as vice president of analytical development and quality control at Akero. He brings over 30 years of experience in the biopharmaceutical industry, building and leading high-performing analytical development teams engaged in a broad range of biologics programs from early- and late-stage development through commercial launch. Under his leadership, these teams provided comprehensive analytical expertise in molecule assessment, extended product characterization, method development and validation, process development and validation, as well as manufacturing investigations and troubleshooting. Prior to joining Akero, Dr. Kao held scientific leadership roles at Genentech, CytomX Therapeutics, and Vir Biotechnology. Born and raised in Taiwan, Dr. Kao earned his B.S. in Chemistry from National Tsing Hua University in 1986 and his Ph.D. in Chemistry from Pennsylvania State University in 1994.

Seth L. Harrison, M.D.

Independent Board Member

Seth Harrison is founder and managing partner of ATP (Apple Tree Partners), a leading life sciences venture capital firm with $2.65 billion in committed capital. To date, ATP has launched or invested in more than 30 transformative companies focused on delivering cutting-edge therapies for unmet medical needs, out of which 19 so far have gone public or been acquired. Prior to starting ATP in 1999, Seth was a general partner at Oak Investment Partners, and before that a venture partner at Sevin Rosen Funds. From 2002 to 2010, Seth also served on the board of the International Partnership for Microbicides. Seth received an AB from Princeton University and an M.D. and MBA from Columbia University, and completed a surgery internship at the Presbyterian Hospital in New York City.

Scott Gangloff

Chief Technical Officer

Scott Gangloff is chief technical officer of Akero. He brings 28 years of experience in biopharmaceutical development and manufacturing and has led these aspects for numerous products, leading to several biologics approvals in the US, Europe, and other global markets for oncology and immunology programs. Scott joined Akero from Incyte Corporation, where he served as vice president, global biopharmaceutical development, responsible for CMC development and supply-chain activities for the large molecule pipeline. Scott also has built bioprocess, pharmaceutical development, and manufacturing teams in both the start-up and large pharma environments at Oncobiologics and Bristol-Myers Squibb. Scott holds a master of engineering in chemical engineering from Lehigh University.

Tom Heyman

Independent Board Member

Tom Heyman has a long-standing track record of leadership and management in the biopharmaceutical industry, with particular experience in business development and venture capital. Spanning his 37-year career with Johnson & Johnson, Tom held a diverse range of leadership roles across legal, R&D, business development, general corporate management, and equity investments. Previously, he served as president of JJDC, the venture capital group within Johnson & Johnson, where he managed approximately $1.5 billion of capital and oversaw investments in more than 120 companies. Prior to his time at JJDC, Mr. Heyman spent 23 years leading business development for Johnson & Johnson’s pharmaceutical group, Janssen. Tom currently serves on the Board of Directors of Adagio Therapeutics. Tom graduated as master of law from the K.U. Leuven in Belgium. He continued with post-graduate studies in International Law in Geneva, Switzerland, and post-graduate studies in business management at the University of Antwerp in Belgium.

Yuan Xu, Ph.D.

Independent Board Member

Yuan Xu has a long-standing track record of executive and scientific leadership in biopharmaceutical research, development, manufacturing, commercialization, and life-cycle management. Most recently, she served as a board member and chief executive officer for Legend Biotech Co., playing a leading role in its successful IPO. Dr. Xu’s prior career as a senior executive includes heading up Merck’s Biologics and Vaccines subdivision, as well leading biopharmaceutical development and manufacturing groups for Novartis, Gilead, and GlaxoSmithKline. Yuan currently serves on the board of directors of Fate Therapeutics and the scientific advisory board and manufacturing advisory board of National Resilience, Inc. Dr. Xu received a B.S. in biochemistry from Nanjing University and a Ph.D. in biochemistry from the University of Maryland. She completed her post-doctoral training in virology and gene therapy at the University of California, San Diego.
Akero employee smiling and talking to a man in a conference room

We’re always looking for talented individuals driven to make a difference for patients.