Restoring Metabolic Balance.

Transforming Lives.

Developing medicines to reverse the course of serious metabolic diseases.

NASH: A Life-Threatening Liver Disease

NASH (non-alcoholic steatohepatitis) is rapidly emerging as the leading cause of liver disease around the world, driven by the growing global epidemic of obesity and diabetes. NASH is a severe form of non-alcoholic fatty liver disease (NAFLD) characterized by liver cell (hepatocyte) damage, liver inflammation, and fibrosis that can progress to cirrhosis, liver failure, cancer and death.

Abstract Illustration of Liver
Illustration of AKR-001

Our Lead Candidate: AKR-001

AKR-001 is an investigational treatment for NASH being evaluated in a Phase 2 clinical trial. AKR-001 is engineered to harness the inherent benefits of a naturally-occurring hormone called FGF21 with once-weekly subcutaneous dosing. AKR-001 addresses both the underlying metabolic drivers of NASH and the downstream consequences of inflammation and fibrosis.

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Delivering Transformational Therapies for Patients

Akero Therapeutics is a clinical-stage company led by a team of industry veterans dedicated to developing transformational therapies for serious metabolic diseases. Our initial focus is NASH, a serious and rapidly-growing condition for which there is no approved treatment.

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In the News

May 29, 2019

Akero Therapeutics Initiates Phase 2a Clinical Trial of Investigational Therapy AKR-001 for the Treatment of NASH

Akero Therapeutics announced today that it has screened the first patient for its Phase 2a clinical trial evaluating AKR-001, the company’s lead product candidate for the treatment of NASH.

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May 1, 2019

Akero Therapeutics Appoints Bill White as CFO and Head of Corporate Development

Mr. White joins Akero from Deutsche Bank, where he was a Managing Director and Head of U.S. Life Sciences Investment Banking…

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April 23, 2019

Akero Therapeutics Appoints Industry Veteran Jane Pritchett Henderson to Board of Directors

Ms. Henderson brings over 30 years of biotech industry experience in capital raising, business development and operations…

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January 4, 2019

Akero Therapeutics to Present at the 37th Annual J.P. Morgan Healthcare Conference

Akero Therapeutics announces that the company will present at the 37th Annual J.P. Morgan Healthcare Conference in San Francisco, CA.

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December 12, 2018

Akero Therapeutics Announces $70 Million in New Financing

Akero Therapeutics announces the company has closed $70 million in new financing, which will support the advancement of Akero’s lead clinical candidate AKR-001.

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December 6, 2018

Akero Therapeutics Appoints Mark Iwicki to its Board of Directors

Akero Therapeutics today announced the appointment of Mark Iwicki, chairman and CEO of Kala Pharmaceuticals, to Akero’s Board of Directors…

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